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FIGURE 6 4 Discussion NAFLD is a metabolic disease that disrupts body fat metabolism, increases the production of active oxygen, causes oxidative stress, and elicits an inflammatory response (Paradies et al., 2014)

10.1016/j.phymed.2016.02.005 34 LevinS

403,404,405 The three stress sensors are inositol-requiring enzyme 1 (IRE1, also known as ERN1), PKR-like ER kinase (PERK, also known as EIF2AK3), and activating transcription factor 6 (ATF6) (Fig
Parkinson's disease, schizophrenia, and addiction are disorders linked to dopamine deficiency, which are either synthesized or metabolized by certain bacteria (Rekdal et al., 2020)

A more recent study in 5-week-old SHRs utilised Ussing chambers for assessing colonic permeability [94]

The samples were stained with 2% uranyl acetate saturated alcohol solution followed by 2.6% lead citrate solution
