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doi: 10.1089/acm.2006.12.857 13 VercoulenJ

J Pharmacol Exp Ther

AOD-9604 has human clinical trial data and FDA GRAS status

Avoid mixing copper peptides with strong, lowpH actives like highstrength vitamin C (ascorbic acid), aggressive AHAs/BHAs (glycolic, lactic, salicylic acid), and potent retinoids in the same step, as they can destabilize peptides or increase irritation

The amount of drug reaches the circulation, the effects are stronger

Some patients may achieve adequate glycemic control or weight loss at this dose level, particularly those with mild metabolic dysfunction or those who are particularly sensitive to the medications effects