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Second, the niosomal bilayer structure enables controlled and sustained drug release, as the vesicles gradually release their cargo over an extended period rather than releasing it all at once [122,124]

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The human dopamine transporter (hDAT) contains a high-affinity, extracellular, and allosteric Zn 2+ (zinc ion) binding site which, upon zinc binding, inhibits dopamine reuptake, inhibits amphetamine-induced hDAT internalization, and amplifies amphetamine-induced dopamine efflux

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Everyone's biochemistry is unique, but given the scientific research, we'd recommend starting with acetyl-L-carnitine