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P450 enzymes are involved in the conversion of methionine to SAMe, which is a critical component of the methylation pathway
10.1007/s00406-004-0456-7 [DOI] [PubMed] [Google Scholar] 21.Rose S, Melnyk S, Pavliv O, Bai S, Nick TG, Frye RE, et al

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The mice were specific pathogen-free (SPF) and about 8 weeks old, weighing 20 2 g
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