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For example, global inhibition of lactate production prevented remyelination in the corpus callosum after experimental demyelination in mice (~3-months-old), while OPC-rich primary cell cultures displayed heightened differentiation when lactate was added to the glucose medium (Ichihara et al., 2017)

Papakyriacou, I

24, 25 Thus, it is tempting to speculate that CDDP resistance might involve specific changes in the immunopeptidome of neoplastic cells as well as in the tumor microenvironment that prevent the activation of anticancer immune responses

Nerve Pressure: When a posterior fibroid grows large, it can press directly against the nerves of the lower back and the sacral plexus

RMD Open 2 , e000282 (2016)

Effect of low doses of herbicide paraquat on antioxidant defense in Drosophila