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TP53 is the most frequently mutated gene in high-grade serous ovarian cancer, and the majority of these mutations result in overexpression of mutant p53

Animal models of myocardial infarction show that TB-500 administration improves left ventricular function, reduces infarct size and cardiomyocyte death during ischemic events, and enhances cardiac microvascular density to improve tissue perfusion

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Owing to the metabolic reprogramming of tumor cells, many nutrients, including glutamine, are necessary for tumor cells to maintain their rapid growth and high metabolic demand