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With regular use, it contributes to a more plump, resilient, and healthy-looking complexion. How to Use for Best ResultsAfter cleansing, apply an appropriate amount to your face and neck, gently massaging in upward motions until fully absorbed

Trial registration The study protocol was approved by the ethics committee of Guilan University of Medical Sciences (IR.GUMS.REC.1400.197) in accordance with the World Medical Associations code of ethics (Declaration of Helsinki, revised in Brazil 2013), and registered at an ICMJE and WHO recognized registry of clinical trials ( www.irct.ir ) on 28/08/2021 (registration number: IRCT20200920048782N1).

A potential downside of taking metformin is the link between long-term use and vitamin B12 deficiency

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