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Some people take anti-fever medications like ibuprofen, acetaminophen and aspirin before a shot

J Feline Med Surg 23(6), 513-518

There is no clinical consensus on timing
doi: 10.1111/j.1749-6632.1988.tb23886.x

Active-form methylcobalamin circumvents that bottleneck and supports more predictable cellular uptake
