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[DOI] [PMC free article] [PubMed] [Google Scholar] 84.Asma B., Vicky L., Stephanie D., Yves D., Amy H., Sylvie D

Moreover, relative to the surge in TNF- levels, IL-10 forms a relatively deficient level, rendering it incapable of counteracting the severe excessive inflammation. As the disease progresses, particularly in RMPP, this compensatory mechanism breaks down, manifested by the inability to maintain IL-10 levels or even a significant decrease, highlighting its anti-inflammatory deficiency (141)