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[DOI] [PMC free article] [PubMed] [Google Scholar] 39.Vreugdenhil AC, Wolters VM, Adriaanse MP, Van den Neucker AM, van Bijnen AA, Houwen R, Buurman WA

Research has found that the main role of NAD+ within the body is to transfer electrons from one molecule to another

Epithalon is a synthetic peptide made of just four amino acids (Alanine-Glutamic-Aspartic-Glycine)

They found that ASAH2 inhibition in colorectal cancer cells leads to decreased GSK3 phosphorylation and activation of AKT, a critical cell growth target

However, in chronic white matter lesions, OPC differentiation into OLGs like that observed in early active lesions does not occur (Kuhlmann et al., 2008), suggesting that inhibitory factors block differentiation

Wuertz, K., Godburn, K
