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iScience 26 , 107044 (2023)

2B) and 5-HT (1.3-fold, 1.9-fold, and 2.1- fold, respectively) (Fig

These alterations result from generation of highly reactive free radicals leading to peroxidation of membrane phospolypids rich in polyunsaturated fatty acids, particularly in conditions with increased intracellular iron and decreased antioxidant systems (namely glutathione) (Hirschhorn and Stockwell, 2019)

Growth curve of body weight of nude mice after MSCs Exo treatment (n = 4-8 tumors/group)

It is anticipated that nano-drugs will emerge as a viable method for diagnosis, imaging, as well as the treatment and control of diverse diseases, representing a significant advancement in the modernization of natural product research

Interestingly, by strategically leveraging the biological functions of microorganisms, these organisms can, under appropriate conditions, use environmental substances to construct corresponding nanomaterials, which are categorized as extracellular and intracellular based on their site of synthesis [101]