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To further prove the influence of intracellular GSH level on the cytotoxicity of NSBSO, we pre-treated 4T1 and B16 cells with GSH synthesis inhibitor to reduce the intracellular GSH level, and the results showed that the pretreatment of the inhibitors gradually reduced the intracellular GSH to a very low level after 24 h treatment (Additional file 1: Fig

Collectively, these changes suggest a reduced cardiovascular risk over the course of the 24-week intervention

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Permeabilization in Mller glia cells depends on P2X7 receptor

Plasma levels of liver enzymes (ALT, AST, ALP), and triglycerides all decreased, and MRI showed decrease hepatic steatosis

Recall the area under the curve is the probability