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doi: 10.1001/jama.2009.2014
It might be because of fewer platelets made in the bone marrow, more platelets being removed, or because of spleen or liver issues

Such research could validate skin pigmentation changes as a valuable tool for early detection of CLD

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Some studies suggest that very long-term use (years of high doses) could potentially lower zinc levels

At present, among non-pharmacological options, physical rehabilitation has shown effectiveness in improving functional recovery after stroke [8]
