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10.1002/jcp.28632 113 LiuJ.ZhangC.LinM.ZhuW.LiangY.HongX.et al (2014)

In practice, potential benefits are not universal: it depends on the context (diet, nutritional status, training level or medical conditions)

It helps to regenerate Vitamin E and glutathione

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These findings should be viewed as hypothesis-generating , providing a systems-level context for the observed metabolite changes rather than evidence of causal normalization

Skin lightening creams and intravenous or oral glutathione do not offer reasonable clinical benefit over placebo effect, are not associated with long term improvements, harbor potential adverse events (heavy metal toxicity and renal injury) or lack safety data (intravenous glutathione) and hence, not recommended (98100)