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Data availability Researchers can access the original dataset by creating an account on and after completing the necessary steps to obtain permission for the MIMIC-IV database (version 2.2), which is available on To receive permission, researchers must complete the CITI data or specimens only research training course and sign the PhysioNet data use agreement for credentialed health data

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Med Clin North Am 106:349363

Sleep deprivation triggers mitochondrial DNA release in microglia to induce neural inflammation: preventative effect of hydroxytyrosol butyrate

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[2] Additional subunits The quaternary structure of the pyruvate dehydrogenase complex is further complicated, as mentioned previously, by the presence of three additional subunits: a pyruvate dehydrogenase kinase, a pyruvate dehydrogenase phosphatase, and the E 3 -binding protein (E3BP)