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42 Activation of TRIMK21 catalyzes K63-ubiquitin chain formation, thereby stimulating transcription factor pathways involving NF-B, AP-1 and IRF3, IRF5, IRF7

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These secondary metabolites have pharmacological uses in treating diabetes, arthritis, bladder infections, cancer, and inflammation, but there is still a lack of conclusive scientific data (Batiha et al., 2020