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Emerging Microbes & Infections

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Notably, some populations of AMs might adopt a mixed or alternative (M2-like) activation state, potentially relying on oxidative phosphorylation to varying degrees, which could paradoxically contribute to impaired bacterial clearance and fibrotic repair processes, thus driving disease progression

doi: 10.1038/nrdp.2018.17 37 ChelakkotCGhimJRyuSH

Trials report administering the peptides late in the evening, usually at bedtime

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