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Diagnostic procedures commonly utilized include: Brush biopsy/scrape cytology : A minimally invasive technique to collect cells for microscopic examination Incisional biopsy : Removal of a small tissue sample for definitive histological diagnosis Imaging studies : CT scans, MRIs, or PET scans may be ordered to assess the extent of suspicious lesions and potential spread For pigmented lesions specifically, doctors will determine if they can be wiped away, which might indicate conditions like oral candidosis rather than true pigmentation

doi: 10.1016/j.celrep.2016.10.037

doi: 10.1038/s41467-018-07705-w 247 TamburiniE.DallatomasinaA.QuartararoJ.CortelazziB.MangieriD.LazzarettiM.et al

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