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Important caveat: Side effect data comes primarily from animal studies

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Therefore, a deeper understanding of hostpathogen interactions is required to elucidate and validate potential HDTsfor example, recent studies have focused on diverse mechanisms that enhance intracellular survival, including foamy cell induction, modulation of autophagy and phagosome maturation, control of cell death, and manipulation of inflammasome activation in macrophages (262)

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