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Specifically, we systematically dissect the multifaceted roles of lactate and lactylation through the lens of five distinct pathological pillars of PH: (1) aberrant proliferation of pulmonary artery smooth muscle cells (PASMCs), (2) dysregulated immune-inflammatory responses, (3) progressive pulmonary fibrosis, (4) abnormal vasoconstriction, and (5) PASMC ferroptosis

Nutrients 6: 466-488

These results highlight the complexity of cellular responses to chemotherapeutic agents and antioxidants

The convenience of a capsule can sometimes lead to laxity

The role of thiamine in neurophysiology The role of thiamine in nervous tissue: effect of antimetabolites of the vitamin on conduction in mammalian nonmyelinated nerve fibers Acetylcholine: How and Why to Optimize the Synthesis of this Vital Neurotransmitter Pharmacologic treatments for the behavioral symptoms associated with autism spectrum disorders across the lifespan