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To verify the key role of GSH response in inducing pyroptosis, we compared the expression of GSDMD and GSDME in 4T1, B16 and CT26 cells

Both LC and TMZ intervention ameliorated HUA-associated decreases in stroke volume, as did AP intervention (Figure 6L)

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Additionally, increased activity of PHGDH facilitates the transition of macrophages to the immunosuppressive M2 phenotype

Natural polyphenols generate, in the presence of increased metal concentrations ( Figure 4) [10,97,100] or activated NADPH: quinone oxidoreductases, superoxide and semiquinone radicals and thus exhibit a strong pro-oxidative effect