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Aging and bone loss Adverse effects of aging are, in part, attributed to decreases in mitochondrial function and increases mitochondrial oxidant production [141]

This results in the accumulation of electrons which can trigger ROS generation, as well as an accumulation of acyl-CoA which further disrupts mitochondrial function and signaling

[DOI] [PubMed] [Google Scholar] 213.Shrimanker I, Bhattarai S

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