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M., Carneiro-Freire, N., Seco-Filgueira, M., Fernndez-Fernndez, C

(More information) Acquisition of the gut microbiota begins at birth, its community structure continues to develop and diversify throughout childhood, and it stabilizes during the teen years

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Moreover, dietary supplementation with TMAO significantly decreased the expression of both enteral cholesterol transporters Niemann-Pick C1-like1 (Npc1L1), which transports cholesterol into enterocytes from the intestinal lumen, and ABCG5/8, which transports cholesterol out of enterocytes into the gut lumen ( The TMA/FMO3/TMAO pathway driven by gut microbiota is also an important regulator of lipid metabolism (Warrier et al., 2015)