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Description
Dihexa is not a conventional peptide but a peptidomimetic a small molecule (~504 Da) designed to mimic peptide binding activity while resisting enzymatic degradation

Clinical Uses Vitamin B12 injections are used to treat or prevent B12 deficiency in various situations: Pernicious anemia: An autoimmune condition where gastric intrinsic factor is missing

Mechanistic modules Add transcriptomics/epigenomics of muscle and liver, mitochondrial respirometry, and metabolomics for pathway resolution

The switch involves two changes simultaneously: the B12 form (cyanocobalamin to methylcobalamin) and the delivery method (injection to oral)

Infante M, Leoni M, Caprio M, Fabbri A (2021) Long-term metformin therapy and vitamin B12 deficiency: an association to bear in mind

Symptoms such as skin rashes, itching, and gastrointestinal discomfort may occur after taking B12 supplements or consuming fortified foods
