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The obsessions or compulsions must cause marked distress, be time-consuming, or significantly interfere with social or occupational functioning, in order to meet the DSM-III-R (circa 1989) diagnosis of OCD

doi: 10.7759/cureus.52153

Systemic adverse effects: Contemporary radiology and endocrine reviews catalogue adrenal suppression , hyperglycaemia , hypertension , osteoporosis , skin changes , facial flushing and moreeven after local delivery

Magnesium stearate (4.5 mg) is a standard stabilizer with no reported issues at this level

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Key nutritional factors: Adequate protein intake, typically 0.7-1g per pound of body weight during healing