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The proposed primary mechanism involves augmentation of hepatocyte growth factor (HGF) / c-Met receptor signaling, with downstream activation of MAPK, PI3K-Akt and the canonical synaptic-protein-synthesis machinery [2]

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Tetrahydrofolic acid, methyltetrahydrofolate, and other folic acid congeners are essential for the maintenance of normal erythropoiesis and are also required cofactors for the synthesis of purine and thymidylate nucleic acids

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10.1002/jcp.21706 185
