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29,30 These observations revealed that loss of Nf1 gene expression in SKPs is required, but not sufficient, for neurofibroma development, and revealed critical roles for the tumour microenvironment

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cAMP-responsive element-binding protein 1 is a potent activator of PGC-1 and, thereby, initiates the synthesis of mitochondrial and respiratory chain proteins (Tengan et al., 2012

Cysteine is the rate-limiting precursor for the biosynthesis of GSH, which is one of the primary antioxidants within cells and essential for protecting retinal cells from oxidative stress and ferroptosis