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Importantly, Munc18-1 Q301D expression in Munc18-1 deficient neurons severely reduces synaptic transmission, demonstrating the physiological significance of the Munc18-1VAMP2 interaction.

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In this review, we briefly introduce the aetiology and epidemiology of several fibrosis diseases, including liver fibrosis, kidney fibrosis, cardiac fibrosis, and pulmonary fibrosis

The balance of prooxidants and antioxidants in the human body is heavily reliant on an adequate supply of dietary micronutrients. Important antioxidant enzymes like superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) require cofactors in the form of trace minerals that include selenium, zinc, iron, manganese and copper to function optimally as our first line of defense against reactive oxygen species (chemically reactive molecules that contain oxygen

What is the main difference between salicylic acid and glycolic acid

DNA damage response (DDR) is a series of regulatory events including DNA damage, cell-cycle arrest, regulation of DNA replication, and repair or bypass of DNA damage to ensure the maintenance of genomic stability and cell viability