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For example, the humanized monoclonal antibody Eculizumab (targeting C5), an approved drug, has established its safety profile in diseases such as paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome (106)

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[DOI] [PMC free article] [PubMed] [Google Scholar] Pagano C, Calarco P, Ceccarini MR et al
