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Intraoral manganese superoxide dismutase-plasmid/liposome (MnSOD-PL) radioprotective gene therapy decreases ionizing irradiation-induced murine mucosal cell cycling and apoptosis

N Engl J Med 2004, 351 (16):1692-1693

Discontinue use immediately if hypersensitivity or adverse reactions occur.

Postoperative tumors typically present an immunosuppressive microenvironment

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For this, the ammonium sulfate solution was replaced by a 50-100 mg/mL solution of the peptide, leading to peptide encapsulation in the water core of the liposome with efficiencies of about 15% and a stable formulation