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One-vs two-phase extraction: re-evaluation of sample preparation procedures for untargeted lipidomics in plasma samples

evaluating the consistency of diet-induced metabolite signatures throughout the intervention to assess potential metabolic adaptation

Our analysis, covering more than 200 ns per trajectory, indicates that lipid II increases not only the stability of the nisin pore, but that its interaction with nisin also leads to local changes in thickness and viscosity within bacterial membranes, ultimately weakening their integrity

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doi: 10.1016/S0014-5793(00)02332-2