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Certain flavonoids can even promote neuronal recovery: fisetin, quercetin, luteolin, and others have been observed to induce neurite outgrowth and synaptic marker expression, suggesting a capacity to support neural regeneration, although this requires continuous presence of the compounds and appears dose-dependent (9)

[DOI] [PubMed] [Google Scholar] 125.Rydstrm J

Studies also show that alcohol abuse affects the volume of grey matter in the brain, causing its reduction

doi: 10.1002/agm2.12363 287 LeeJHLeeMS

IV, Intravenous

Consequently, the anti-inflammatory M2 macrophages are converted to pro-inflammatory M1 macrophages, causing a cytokine storm known to cause endothelial tissue and organ damage in severe COVID-19 patients