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Notably, L2HG-induced ferroptosis occurs independently of impaired cystine uptake, transsulfuration pathway activity, or increased GPX4-mediated GSH utilization, revealing a non-canonical ferroptosis mechanism driven by enhanced GSH catabolism

Fish were fed these diets for 70 d, after which a 96-h hypoxic stress experiment was conducted

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MDD is especially burdensome as approved monoamine antidepressant treatments have weeks-long delays before ...