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Anticonvulsant mechanisms of the ketogenic diet and caloric restriction

Histone acetylation is catalyzed by histone acetyltransferases or removed by histone deacetylases

Under conditions of non-elevated homocysteine and adequate B vitamin status, there is little or no expectation that additional supplementation will further reduce disease risk

doi: 10.1016/j.freeradbiomed.2024.11.021 42 EltokhyAKEl-ShaerRAAEl-DeebOSFarghalEEIbrahimRRElesawyRet al

The mammalian enzyme is a hexamer of identical subunits, suggesting allosteric regulation of activity (much like tetrameric hemoglobin)

2018 Jan 6;58:353-389
