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Furthermore, exercise promotes the upregulation of angiogenic factors mostly prominently VEGF from myocytes and endothelial cells, thereby fostering capillary proliferation and remodeling that are essential for sustained long-term perfusion (17)

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635 A double-blind, randomized, placebo-controlled trial of LX-9211 for pain relief and safety in DPN initially found that LX-9211 improved PDPN

doi: 10.1210/clinem/dgaa057 283

J Endocrinol 238:R79R94