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PMID 41500720

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Excess accumulation of Fe, Cu, and Zn in the AD brain enhances oxidative stress, facilitates A aggregation, and promotes tau hyperphosphorylation (Eisenstein, 2000)

It has been suggested that the powerful physiological antioxidant actions of bilirubin are a result of an amplification cycle whereby bilirubin acting as an antioxidant, is itself oxidized back to biliverdin and then recycled back to bilirubin via biliverdin reductase (33)

TEM is a mechanism by which endothelium may play a role in COPD and therefore may be important in the development of inflammation and in the pathogenesis of COPD

Major Probl Clin Pediatr 10:1478 Nguyen T-L, Durn RV (2018) Glutamine metabolism in cancer therapy