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In preclinical research models, MOTS-C has been shown to translocate to the nucleus in response to metabolic stress, where it regulates the expression of antioxidant and metabolic response genes
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[3] Fernndez-Lzaro, D., Domnguez-Ortega, C., Busto, N., Santamara-Pelez, M., Roche, E., Gutirez-Abejn, E., & Mielgo-Ayuso, J
doi: 10.23750/abm.v89i8-S.7947 61 KeenanJ
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