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#Pharmacology #NSAIDs #ClinicalPharmacy #PharmaceuticalScience #DrugMechanism #PharmacyStudents #MedicalEducation To view or add a comment, sign in Medical Alert: A Dangerous Drug Combination That Could Trigger Seizures A new study has found that combining Tramadol, a commonly prescribed painkiller, with certain antidepressants (such as Fluoxetine, Paroxetine, Sertraline, and Bupropion) can significantly increase the risk of seizures, especially in older adults

This is why USP 797 assigns conservative default BUDs and requires pharmacies to provide supporting data before extending those dates

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