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Because this formula contains niacinamide, a few people might experience a flushing reaction (warmth, redness of the skin) or slight itching, although niacinamide usually does not cause the intense skin flush that niacin (nicotinic acid) does
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Furthermore, the research supporting systemic (injectable) GHK-Cu for tendon or joint repair in healthy humans is almost non-existent, relying entirely on animal models and anecdotal reports

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