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Medical supervision is not just recommended

According to Cant et al., Cell Metabolism , increased NAD stimulates PGC-1 activity, driving mitochondrial biogenesis and substrate flexibility

doi: 10.1242/dev.200750 206 SatarkerS.BojjaS

When managed by a qualified medical professional, semaglutide and tirzepatide are safe and effective for metabolic optimization and weight loss

Bristow MR, Thompson PD, Martin RP, Mason JW, Billingham ME, Harrison DC

44 , 32103230 (2025): Ma, S
