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How AOD-9604 Works: Beta-3 Adrenergic Signalling and the cAMP Pathway AOD-9604 activates fat cell lipolysis by binding to beta-3 adrenergic receptors on adipocyte membranes, triggering cAMP-mediated activation of hormone-sensitive lipase, which then cleaves stored triglycerides into free fatty acids

Elevated NNMT is linked to: Reduced NAD+ availability Slower mitochondrial function Increased fat storage efficiency Higher risk for insulin resistance By reducing NNMT activity, 5-Amino-1MQ allows the body to maintain higher NAD+ levels, which can support better mitochondrial performance, improved fat oxidation, and more balanced energy metabolism