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Immune system to brain signaling: Neuropsychopharmacological implications

Following this pattern, TMEV-infected SJL/J mice treated orally with this same antibiotic mixture showed protection against motor dysfunction, axonal damage, and CNS immune infiltration, likely through enhanced CD4 + CD39 + T cells, CD5 + CD1d + B cells, and downregulated IL-17 in the periphery (Mestre et al., 2019)

[DOI] [PMC free article] [PubMed] [Google Scholar] 130.Vlasova K.Y., Ostroverkhov P., Vedenyapina D., Yakimova T., Trusova A., Lomakina G.Y., Vodopyanov S.S., Grin M., Klyachko N., Chekhonin V., et al

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Schisselbauer JC, Silber R, Papadoupoulos E, Abrams K, LaCreta FP and Tew KD