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Calabrese and Halpain, 2024)

Both creatine and creatine phosphate are found in muscle, brain, and blood

The barrier tightness of the model was verified by transendothelial electrical resistance (TEER) measurements using an EVOM voltohmmeter (World Precision Instruments, USA) combined with STX-2 electrodes

Moreover, research has indicated that these polyphenols effectively alleviate oxidative stress and organ damage caused by hyperglycemia (Myint et al., 2020)

doi: 10.1021/tx050076e

Therefore, genetic screening can be performed in the clinical application of cisplatin to identify high-risk groups, and otoprotective agents or platinum replacement drugs can be used in advance to prevent damage in cisplatin-sensitive patients (Lee et al., 2016a)