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10.1038/s41556-018-0124-1 Nat

Regarding the role of the genetic variability of GSTM1 and GSTT1 in alcohol consumption, there is one study that included patients with hepatocellular carcinoma, indicating the influence of the GSTM1 null genotype in the high ethanol intake [90]

[DOI] [PubMed] [Google Scholar] 27.Wijmenga C, Klomp LW

Oxidative Med Cell Longev 2017:45351944535118

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The transfer of electrons along the enzymes of the respiratory chain is not totally efficient, and leakage of electrons onto molecular oxygen, in particular from complexes I and III, results in the formation of superoxide anion [41, 42]
