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Vitamin C function in the brain: vital role of the ascorbate transporter SVCT2

Lipidomics analysis by LCMS HEK 293T cells expressing the indicated constructs were illuminated for 30 min with intermittent blue light (470 nm, 5-s pulses every min) and rinsed once in PBS

Iwashita, S., Williams, P., Jabbour, K., Ueda, T., Kobayashi, H., Baier, S., & Flakoll, P

Limitation: direct measurement of intracellular NAD+ in different tissues in humans is technically challenging

However, for such brown spots Cryotherapy is as effective as using laser but more reliable, less expensive and less likely to cause side effects.