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S.PeterE.RothbartM.SchlickeH.ToivolaJ.RintamakiE.et al

doi: 10.1016/S0021-9258(19)85901-X

And FDA regulators agreed, saying later that the substances present significant safety risks, because most have not been extensively tested in humans

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Weight-based dosing offers an alternative approach at approximately 0.085 mg per kilogram of body weight per week
