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Molecules this large face fundamental barriers to transmucosal absorption regardless of the formulation technology used

Cell-culture (3T3-L1 adipocytes) 5-Amino-1MQ at 30 M strongly reduced 1-MNA levels in mouse fat cells, confirming NNMT inhibition (Neelakantan et al., Biochemical Pharmacology, 2018)

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Retrieved July 28, 2024

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