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Managing Side Effects in Research Settings Strategies that have proven effective in clinical trials for managing cagrilintide-related side effects include: Slower titration schedules Extending time between dose increases Meal timing adjustments Taking doses after meals rather than before Hydration optimization Maintaining adequate fluid intake Dietary modifications Smaller, more frequent meals

A longer alternative is 30 days on, 14 days off, repeated as needed

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Some patients notice reduced hunger within the first few weeks of treatment