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The possibility that the ER status of the tumor is associated with the cellular origin emphasizes that profi ling of stem and progenitor cells in normal breast tissues as well as in carcinomas has profound implications for the further development of existing therapies and new strategies for bypassing antiestrogen resistance
otherwise, regulatory actions and sanctions shall be strictly pursued
doi: 10.1089/ars.2012.4742

Liposomal and nano-liposomal delivery systems may enhance these effects by ensuring sustained release and improved uptake of ascorbic acid in the gastrointestinal tract (Farouk et al
(2013) 9:e1003794

[DOI] [PMC free article] [PubMed] [Google Scholar] 65.Rossignol D.A., Frye R.E