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For those with no known deficiencies or contraindications, vitamin B12 shots are often considered unnecessary and may not provide additional benefits

Serum B12 reflects the general amount of B12 stores and is a useful indicator of B12 status although it lacks sensitivity and specificity for diagnosing B12 deficiency (235, 236)

Although a direct causal link between NAD+ supplementation and cancer progression has not been proven, experts recommend that patients with an ongoing cancer or a history of cancer only consider NAD+ therapy with clearance from their oncologist

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Also, 14 common adult procedures and conditions were ranked as high performing: aortic valve surgery, chronic obstructive pulmonary disease (COPD), colon cancer surgery, gynecological cancer surgery, heart arrhythmia, heart attack, heart bypass surgery, heart failure, hip fracture, kidney failure, leukemia lymphoma & myeloma, pneumonia, prostate cancer surgery, and stroke care